Medical, Scientific, and Regulatory Updates
MIKS curates reliable and high-quality information published in the field of regenerative medicine, ensuring you can effortlessly stay current.
Certain news pieces are exclusively available to members. If you wish for unrestricted access to all news articles, you can achieve that by becoming a member of our community. Join as a member today to enjoy complete access to all our content.
16 diciembre 2024
MIKS NEWS
New developments in platelet-rich plasma (PRP): new advances in the integration of extraplatelet molecules to improve its therapeutic efficacy.
In recent years, platelet-rich plasma (PRP) has established itself as a key biological therapy in various medical specialties, especially in the treatment of musculoskeletal pathologies such as osteoarthritis. Its efficacy lies in the concentration of platelets, which release growth factors essential for tissue repair and regeneration. However, recent research has revealed that plasma molecules outside platelets also play a fundamental role in these processes.
Despite significant advances in the field of PRP, traditional centrifugation-based techniques are not able to adequately concentrate these extraplatelet molecules, thus limiting their therapeutic potential. Faced with this challenge, the research group of the Arthroscopic Surgery Unit (UCA) has focused its efforts on the development of innovative methods that allow not only the concentration of platelets, but also of these plasma molecules.
As a result of these studies, the UCA group has developed three techniques that balance the levels of platelet and extraplatelet molecules, obtaining a new generation PRP with greater biological activity. Laboratory tests have shown that this improved PRP could have a more potent therapeutic capacity, suggesting a greater potential in the treatment of various pathologies.
This work, which includes a doctoral thesis in collaboration with the UPV/EHU, has resulted in five publications in high-impact scientific journals. The findings stand out for their relevance in the field of PRP-based therapies, promising a significant evolution towards more effective and personalized treatments.
For more information, please check the following links:
- Method based on ultrafiltration to obtain plasma-rich platelet and plasma growth factors
- New formulation of platelet-rich plasma enriched in platelet and extraplatelet biomolecules using hydrogels
- Method to obtain a plasma rich in platelets and plasma growth factors based on water evaporation
- New formulations of platelet-rich plasma: the relevance of extraplatelet molecules
- Current challenges in the development of platelet-rich plasma-based therapies
This development represents a crucial step towards more effective and personalized treatments in the field of tissue regeneration.
Image gallery